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Healthy mitochondrial function is vital for healthy aging.5

4.2 Prebiotics as critical modulators of gut-thyroid homeostasis Prebiotics, indigestible dietary fibers that selectively stimulate the growth and activity of beneficial gut bacteria, serve as essential adjuncts to probiotic therapy and independently contribute to hypothyroidism management (Ouyang et al., 2024)

Consistently, the protein expression levels of HO-1, Nrf2, and Keap1 were also significantly increased in the DZN-treated group compared to those in the control group (Fig